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Description of  The Effects of Estrogen on Brain Function

This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be elucidated. Among the topics discussed:" Preclinical data on estrogen's effects on cognitive performance" The short-lived effects of hormone replacement therapy on cognitive function" Structural and functional brain imaging data regardingestrogen's effects on the central nervous system " Preclinical efforts to develop effective NeuroSERMs for the brain " The effects of estrogen on mood Citing the ongoing confusion over the risks and benefits of estrogen therapy, the contributors emphasize the need for additional research on medication, doses, preparations, methods of administration, alternative therapies, and supplements. This volume educates researchers, clinicians, and students on the current knowledge?including the effects of estrogen on mood, cognition, and brain metabolism?and provides guidelines for clinical practice and future research. Contributors: Roberta Diaz Brinton, Ph.D., University of Southern California Cheri L. Geist, B.A., David Geffen School of Medicine, University of California at Los Angeles Robert B. Gibbs, Ph.D., University of Pittsburgh School of Pharmacy Eva Hogervorst, Ph.D., University of Loughborough and University of Oxford Pauline M. Maki, Ph.D., Neuropsychiatric Institute, University of Illinois–Chicago Peter J. Schmidt, M.D., National Institute of Mental Health Daniel H. S. Silverman, M.D., Ph.D., David Geffen School of Medicine, University of California at Los Angeles Katherine E. Williams, M.D., Stanford University School of Medicine Kristine Yaffe, M.D., University of California, San Francisco, and San Francisco VA Medical Center Laurel N. Zappert, B.A., Stanford University School of Medicine Liqin Zhao, Ph.D., University of Southern California